| abstract |
The present invention relates to Rubus coreanus The extracellular signal regulated kinase (VEGF) -derived extracellular signal regulated kinase (ERK), p38, and VEGF-mediated extracellular signal regulated kinase (VEGF) Inhibits VEGF receptor phosphorylation, inhibits VEGF-induced vascular endothelial cell proliferation, inhibits VEGF-induced vascular endothelial cell migration, inhibits VEGF-induced aortic sprouting and inhibits neovascularization, And may be useful for the prevention and treatment of ocular diseases such as diabetic retinopathy, glaucoma, and cancer diseases due to neovascularization. |