abstract |
The present invention provides a novel pyridine derivative, a pharmaceutically acceptable salt thereof, a process for producing the same, and a pharmaceutical composition containing the same as an active ingredient. The pyridine derivatives according to the present invention inhibit the vascular endothelial growth factor receptor (VEGFR2) involved in angiogenesis and all the Raff kinases (B-Raf, Raf-1 and B-RafV600E) Colon cancer, prostate cancer, thyroid cancer, lung cancer, pancreatic cancer, ovarian cancer, and the like. |