| abstract |
The present invention relates to pyridine carboxamide derivatives, a process for their preparation and their pharmaceutical uses. Specifically, the present invention relates to a pyridine carboxamide derivative represented by the formula (I) wherein the substituents of the formula (I) are defined as in the specification, a process for its preparation, a pharmaceutical composition comprising the derivative, In particular as inhibitors of the renal external aqueous potassium channel (ROMK), and in the manufacture of medicaments for the treatment and / or prevention of hypertension and heart failure. |