| abstract |
The present invention provides a novel neuropeptide norketamine (NANKET) compound according to any of the formulas (I - shown below), (IA) and (IB), or any compound described in Table AD or in any of the examples provided herein, And pharmaceutically acceptable salts thereof, novel pharmaceutical formulations thereof and novel methods of use. The present invention also relates to a novel oral neuropeptidated ketamine (NAKET) and neurodestructive controlled release pharmaceutical formulation of NANKET, and a novel method of administration thereof, which comprises administering a therapeutically effective amount of a compound of formula Characterized by ensuring stable release of a therapeutically effective amount of ketamine, norketamine, or a derivative thereof from said orally regulated release pharmaceutical formulation without causing neurologically toxic spikes. |