http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170066429-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_173bc2c63b34988699010ba05e5b1376 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-63 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-80 |
| filingDate | 2015-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bc9b28d84580db4659af39e6b219986 |
| publicationDate | 2017-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20170066429-A |
| titleOfInvention | Process for the preparation of 1-(3,5-dichloro-4-fluoro-phenyl)-2,2,2-trifluoro-ethanone |
| abstract | The present invention provides a process for the preparation of a compound of formula (I), comprising the steps of: a) reacting a compound of formula II with magnesium or a compound of formula III R 1 -M 2 X (III) wherein R 1 is C 1 -C 4 alkyl, M 2 is lithium or magnesium, in the presence of an organometallic reagent of the absent;), a formula IV CF 3 -C (O) -R 2 (IV) ( wherein, R 2 is halogen, hydroxyl, C 1 -C 4 alkoxy, (di -C 1 -C 4 alkyl) amino, OC (O) CF 3, and phenoxy or OM 1; where M 1 is reacted with a compound of lithium, magnesium, being sodium or potassium), to afford a compound of formula V, and b Reacting a compound of formula (V) with an alkali metal fluoride in the presence of a polar solvent in the presence of a catalytic amount of a phase transfer catalyst to obtain a compound of formula (I). (I) ≪ RTI ID = 0.0 & (V) |
| priorityDate | 2014-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.