| abstract |
Problem: Large amount of solvent is required for recovery and purification of teicoplanin, large-scale facilities are required, and it takes time. SOLUTION: The present invention makes it possible to precipitate teicoplanin by making the fermentation broth of teicoplanin under acidic conditions of pH 1.5 to 3.0, and recovering it with a simple process using a water-miscible organic solvent at a high yield. In addition, the present invention can purify teicoplanin with high purity by removing impurities including Teico 2 by washing the Teicoplanin of the modifier sample in an acidic solvent and eluting it. |