| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ae9352b12a967909f871c12337ee3c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3fd4e93602079b4d27116978371b48dd |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-124 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0663
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6881
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 |
| filingDate |
2015-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50b07acc4407ffd7637adb3ce50342a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7f58f13897b3f4fea5daf5df12216d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_267508a760c8baa5ff8c99e5056e10d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f574b2320652b10af032107b27935e50 |
| publicationDate |
2017-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20170055471-A |
| titleOfInvention |
Generation of a mesenchymal stromal cell bank from the pooled mononuclear cells of multiple bone marrow donors |
| abstract |
The present invention relates to an improved mesenchymal stromal cell (MSC) preparation and a method for its preparation. The present invention provides a novel strategy for isolating MSCs from BM-MNCs by pooling a number of unrelated (third-party) bone marrow donors bone marrow mononuclear cells (BM-MNC). MSC preparations made in accordance with the methodology of the present invention are characterized by a stable proliferative capacity and increased immunosuppression potential when compared to a pool of individual MSCs produced from individual donor MSCs or from multiple donors. MSCs prepared in accordance with the present invention are particularly useful for medical applications such as cell-based therapies in regenerative medicine and in the treatment of graft-versus-host disease (GvHD) in hematopoietic stem cell transplant recipients and patients with autoimmune disorders. |
| priorityDate |
2014-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |