abstract |
This disclosure relates to a process for the preparation of N- (4 - {[6,7-bis (methyloxy) quinolin-4-yl] Oxy} phenyl) -N '- (4-fluorophenyl) cyclopropane-1,1-dicarboxamide, and a mixture thereof and a malate salt. The present disclosure also relates to a process for the preparation of one or more N- (4 - {[6,7-bis (methyloxy) quinolin-4- yl] oxy} phenyl) -N ' (4 - {[6,7-bis (methyloxy) quinolin-4-yl] oxy} phenyl) -N '- (4- Fluorophenyl) cyclopropane-1,1-dicarboxamide in the treatment of cancer. |