| abstract |
In particular, pyrazolyl-substituted pyridone compounds exhibiting biological activity, such as inhibitory action, for serine proteases including thrombin and various calicaine are provided. In addition, pharmaceutical compositions are provided. There is further provided a method of treating or preventing a particular disease or disorder, wherein the disease or disorder can be treated or prevented by inhibition of serine proteases, including thrombin and various calicaine. |