| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0619
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5058
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y102-01003 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0793 |
| filingDate |
2015-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2017-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20170047793-A |
| titleOfInvention |
Evaluation method for neurotoxic materials using neuronal cell expressing psa-ncam |
| abstract |
The present invention relates to a method for selecting neurotoxins using neural cells which express polysialylated neuronal cell adhesion molecule (PSA-NCAM). When neural cells differentiated from human embryonic stem cell-derived PSA-NCAM-positive human neural progenitor cell (hNPC^(PSA-NCAM+)) are treated with a neurotoxic substance, cell viability decreases, cytotoxicity is induced, and the growth of neurites is suppressed as well. Accordingly, PSA-NCAM-positive neural cells can be useful in the selection of neurotoxins in vitro. |
| priorityDate |
2015-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |