http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170045539-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a642ee456542d03ca950d862f919344 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-308 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate | 2015-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31cea3d420d2db191d0943530e1c1c55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_229bd062499b5bc6309b1e3cfc2fe601 |
| publicationDate | 2017-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20170045539-A |
| titleOfInvention | A pharmaceutical composition for preventing or treating prostate cancer comprising CACUL1 protein |
| abstract | The present invention relates to a pharmaceutical composition for the prophylaxis or treatment of prostate cancer comprising CAKUL1 (CDK2-associated cullin domain 1) protein, and more particularly to a pharmaceutical composition for prevention or treatment of prostate cancer comprising CACUL1 protein or a polynucleotide encoding the same A pharmaceutical composition for preventing or treating prostate cancer, comprising the composition, the composition and the prostate cancer therapeutic agent, a pharmaceutical composition for inhibiting metastasis of prostate cancer comprising CACUL1 protein or a polynucleotide encoding the same, and a CACUL1 protein or a polynucleotide To a food composition for preventing or ameliorating prostate cancer. The CACUL1 of the present invention inhibits the transcriptional activity of the androgen receptor to inhibit the expression of the target gene and further inhibits the transcriptional activity of the androgen receptor, thereby improving CDX (bicalumide) sensitivity, which is a therapeutic agent for prostate cancer. In addition, CACUL1 has the same effect on metastatic castration-resistant prostate cancer, and thus may be usefully used as a therapeutic agent for prostate cancer and as an agent for inhibiting metastasis of prostate cancer. |
| priorityDate | 2015-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 517.