abstract |
The present application relates to compounds having the general formulas I, II, III, IV, V, VI, IIIa, IIIb, IIIc, IIId, IIIe, IIIf and IIIg. The compounds of formula (I) have the following structure. The compounds of the present application are capable of modulating the activity of histone demethylase (HDME) and may be useful in the prevention and / or treatment of diseases in which genetic control disorders are accompanied by an onset mechanism, for example, cancer. (I) Wherein Q, R 1 , R 18 , R 19 , M, A and Y are as defined herein. |