abstract |
The present invention relates to a skin-whitening composition containing a Piper amide derivative. The Piper amide derivative of the present invention effectively inhibits a melanin synthesis, and also excellently reduces the expression of tyrosinase, tyrosinase-related protein (TRP)-1, TRP-2, and microphthalmia-associated transcription factor (MITF) protein which are associated with melanin formation. Therefore, the Piper amide derivative can be useful as skin-whitening compositions. |