| abstract |
The present disclosure provides antibodies that specifically bind to human glucocorticoid-induced TNFR family-related receptors (GITR) and compositions comprising such antibodies. In particular aspects, the antibody specifically binds to human GITR, modulates GITR activity, and enhances, activates or induces GITR activity using, for example, such antibodies. The disclosure also provides methods of treating or preventing a disorder, such as cancer and an infectious disease, by administering an antibody that specifically binds human GITR and modulates GITR activity, e.g., enhances, activates, or induces GITR activity Provides a method of treatment. |