abstract |
The disclosure of which a) the general formula (I): VH - CH 1 polypeptide chain of -X- V 1; And b) a multispecific antibody molecule comprising or consisting of a polypeptide chain of formula ( II ): VL -CL-Y- V 2 , and a pharmaceutical formulation comprising the same, for use in therapy, for example . The disclosure also provides a polynucleotide sequence encoding the multispecific antibody molecule, a vector comprising the polynucleotide, and a host cell comprising the vector and / or polynucleotide sequence. Methods of expressing multispecific antibody molecules of the disclosure from host cells are provided. |