| abstract |
This disclosure relates to a class of engineered polypeptides having a binding affinity for interleukin-6, wherein the sequences are selected from the group consisting of SEQ ID NOs: EEX 3 X 4 AWX 7 EIH X 11 LPNLX 16 X 17 X 18 QX 20 X 21 AFIX 25 X 26 LX 28 It provides an IL-6 binding polypeptide containing a 29 X. The disclosure also relates to the use of said IL-6 binding polypeptide as a therapeutic, prognostic, and / or diagnostic agent. |