http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170017522-A

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filingDate 2015-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2017-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20170017522-A
titleOfInvention Chitosan-chelator hydrogel for treating cancer and method to prepare the same, and pharmaceutical composition and embolotherapy composition comprising the same
abstract The present invention relates to a radioactive or non-radioactive chitosan-chelator hydrogel and a method for preparing the same, and a composition for cancer treatment and embolization comprising the same as an active ingredient. The chitosan-chelator hydrogel according to the present invention is prepared to have a size of 100-300 m and blocks blood flow toward a tumor tissue to interrupt supply of oxygen and nutrients to the tumor cells, and thus can be used for embolization treatment for cancer tissues. Particularly, a radionuclide-labeled chitosan-chelator hydrogel directly labels a radionuclide or supports a drug upon formation of a hydrogel, and thus has excellent radionuclide labeling efficiency and labeling stability to minimize a free radionuclide. Therefore, a treatment effect of the radionuclide and that of the drug can be expected at the same time, thereby increasing a treatment effect at a focus.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021153823-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180046559-A
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