| abstract |
The use of such peptides in the manufacture of novel compounds of formula (I) and immunoconjugates (i.e., antibody drug conjugates) as described herein are disclosed herein. In addition, immunoconjugates (i.e., antibody drug conjugates) comprising such novel compounds linked to an antigen-binding moiety, such as an antibody, are described herein; Wherein such immunoconjugates are useful for treating cell proliferative disorders. The present invention further provides pharmaceutical compositions comprising these immunoconjugates, compositions comprising an immunoconjugate together with a therapeutic co-agonist, and methods of using these immunoconjugates and compositions for treating cell proliferative disorders. (I) |