http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170011332-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fd6fdb8cc439061143dc8a966303868 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B31-0213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48215 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate | 2015-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82b6ee03ab2c4d9613670fd8c0c21e1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e572bc0ff1aae2ee41e96656527cbbe2 |
| publicationDate | 2017-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20170011332-A |
| titleOfInvention | Globular drug delivery system comprising biocompatible and hydrophilc polymers and uses thereof |
| abstract | The present invention relates to a drug delivery system comprising: a globular nanocage including a fullerene-containing core and a shell containing a biocompatible hydrophilic polymer; and a drug. More particularly, polyethylene glycol (PEG) functioning as a hydrophilic shell is bound to the base structure of fullerene to provide a globular nanocage (globular PEG)-shaped drug delivery system having a hollow central portion, and then chlorin e6 (Ce6) is conjugated with the drug delivery system to provide a globular PEG30-Ce6, which shows higher solubility as compared to the Ce6, improves a singlet oxygen generation level to provide high photoactivity, and realizes reinforced intracellular introduction, thereby providing an increased photodynamic anticancer effect. Thus, the globular PEG30-Ce6 can be used as a photodynamic anticancer agent and the globular nanocage according to the present invention may be used for various medical fields as a drug delivery system. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210047527-A |
| priorityDate | 2015-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.