http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170010797-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_930dbfaf9af0027ba4121c0a7c4288de |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2527-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-117 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-119 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2527-137 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M41-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M29-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M29-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M21-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M29-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M41-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6844 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M41-48 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2015-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a93ebaa2c8c62c462af4f516729945d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ff44caf9d7fdadbf15f2cfb272b8caa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41667bef1403bb6a6f63ee2b3f24890b |
publicationDate | 2017-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20170010797-A |
titleOfInvention | Methods and Means for enhancing RNA production |
abstract | The present invention relates to a method for synthesizing RNA molecules of a given sequence, comprising the steps of: determining the ratio (1) of each of four kinds of G, A, C and U in the RNA molecule; in vitro (in vitro) by transcription includes a step of synthesizing the RNA molecule, wherein the sequences in-and optimized haneung mixture comprises the four types of ribonucleoside triphosphate GTP, ATP, CTP and UTP, the The ratio (2) of each of the four ribonucleoside triphosphates in the sequence-optimized reaction mixture corresponds to the ratio (1) of each nucleotide, buffer, DNA template, and RNA polymerase in the RNA molecule. The present invention also relates to a bioreactor (1) for synthesizing RNA molecules of a given sequence, said bioreactor (1) comprising a reaction module for carrying out in vitro RNA transcription in a sequence-optimized reaction mixture 2), a capture module (3) for temporarily holding the transcribed RNA molecules, and a control module (4) for controlling the infeed of the sequence-optimized reaction mixture component to the reaction module (2) The reaction module 2 comprises a filtration membrane 21 for separating the nucleotides from the reaction mixture and the control of the infiltration of the sequence-optimized reaction mixture components by the control module 4 is carried out by the measurement of the separated nucleoside Lt; / RTI > |
priorityDate | 2014-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 319.