http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170010135-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e4790c814adc8c5a88802341d396009 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-117 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-869 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
filingDate | 2015-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4e7edd4485b131078c842a3b8a5b496 |
publicationDate | 2017-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20170010135-A |
titleOfInvention | Methods to promote differentiation into smooth muscle cells and composition thereof |
abstract | The present invention relates to a method for promoting differentiation into smooth muscle cells and a composition using the same, and more particularly, to a method for promoting differentiation into smooth muscle cells, And inducing overexpression of FGF-12 in the starting cell to change the differentiation state of the starting cell; And confirming the phenotype of the smooth muscle cells in the starting cells. The method of the present invention includes a method of promoting differentiation of smooth muscle cells from a starting cell comprising a polynucleotide encoding FGF-12 as an active ingredient, The present invention relates to a composition for promoting the differentiation of a plant. INDUSTRIAL APPLICABILITY The present invention is very effective in promoting the differentiation of undifferentiated stem cells into smooth muscle cells using FGF-12 as a single factor or promoting the differentiation into smooth muscle cells from fibroblasts. The present invention can easily and efficiently promote the differentiation of smooth muscle cells from various starter cells using FGF-12, and thus can be usefully used for developing a gene therapy agent or a cell therapy agent for smooth muscle cell degenerative diseases. |
priorityDate | 2015-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 587.