| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0624908c7150e45bdd907be4f162057e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c580c97db1b3c46742a810daf2df7779 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-303
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-163
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4748
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57438
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
| filingDate |
2015-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_737216cde604120d969ec441db6febac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5528c844189b3cc01c97d7fc7f1ccd24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf53a89057b464dbd8a7fcd95aecf26a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be658387c41501ea90a92809af8d7386
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b114ca45b1bbba117097497914574774
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fd0ab4848b17307a1615b20fa9d5619 |
| publicationDate |
2017-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20170007671-A |
| titleOfInvention |
A composition comprising antigens for detecting anti-exosomal EIF3A autoantibodies and its application for diagnosing liver cancer |
| abstract |
The present invention relates to a fragment comprising an autoantibody or an antigen-binding site (paratope) specifically binding to an exosomal protein EIF3A (Eukaryotic translation initiation factor 3 subunit A) A hybridoma cell line that produces an immune antibody, a polypeptide having an amino acid sequence of an antigenic determinant site that specifically binds to the autoimmune antibody, a polypeptide having the amino acid sequence of the antigenic determinant site that specifically binds to the autoimmune antibody, A kit for diagnosing liver cancer comprising the composition, and a method for providing information for diagnosis of liver cancer using the composition. The present invention also relates to a method for screening a therapeutic agent for liver cancer using the expression level of the autoimmune antibody. When the anti-EIF3A autoimmune antibody of the present invention is used as a hepatoma diagnostic marker, it is possible to diagnose the incidence of liver cancer to a high level by using a noninvasive biological sample. Further, the amino acid sequence identified in the present invention It is expected to be effective for the development of diagnostic methods such as liver cancer diagnostic kits. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020204665-A1 |
| priorityDate |
2015-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |