abstract |
The present invention provides a multisubstituted pyridine compound of general formula I, a preparation method thereof, a use thereof, and a pharmaceutical composition. The multisubstituted pyridine compounds of the general formula I according to the present invention have excellent antitumor effects, while at the same time inhibiting various cell kinases, have excellent pharmacokinetic properties and are well suited for oral and intravenous administration. The pharmaceutical composition according to the present invention may be useful for treating tumors and cancers. |