abstract |
The present invention also relates to a compound having the structure of the general formula: or a pharmaceutically acceptable salt thereof, a process for preparing the same, and a pharmaceutical composition comprising the compound or a pharmaceutically acceptable salt thereof as a neurogenic disease such as epilepsy, Ischemic stroke, and neurodegenerative diseases. The compound according to the present invention has a better brain tissue absorption effect as compared with retigabine. In addition, the compound of the present invention significantly increases the drug effect, and the neurotoxic side effect remarkably falls as compared with retigabine, and thus has a wider safety window. |