http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160146993-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fb0b2ec1c62686bd1f63f161596afee |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2560-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-912 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2015-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9136e6a7847dc58ba5a6bbc0b940ce7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cf4efa652fead182f929d0c6a2d9fe4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9994d64dbc7ec40c681fccdd513043d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c075c48cb11fd9a727ff299d939be4f |
| publicationDate | 2016-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20160146993-A |
| titleOfInvention | Srm/mrm assay for the tyrosine-protein kinase receptor ufo (axl) protein |
| abstract | The present disclosure relates to tyrosine residues that are particularly advantageous for quantifying AXL proteins directly in biological samples immobilized in formalin by methods of selective-reaction monitoring (SRM) mass spectroscopy, or by methods of multi-reaction monitoring (MRM) - from the protein kinase receptor UFO protein (AXL), specific peptides, and the ionization characteristics of the peptides. Such a biological sample is chemically preserved and fixed, wherein the biological sample is immobilized on a formalin-fixed tissue / cell, a formalin-fixed / paraffin embedded tissue (FFPE) tissue / cell, a FFPE tissue block, ≪ / RTI > and / or tissue cultured cells embedded in paraffin, with formaldehyde-treated tissues and cells containing agonist / fixative. Protein samples are prepared from the biological samples using liquid tissue reagents and protocols, and AXL proteins are quantified in liquid tissue samples by the method of SRM / MRM mass spectrometry by quantifying at least one of the described peptides in a protein sample. If these peptides are present in a modified or unmodified form, these peptides can be quantified. An example of a modified form of the AXL peptide is phosphorylation of the tyrosine, threonine, serine, and / or other amino acid residues in the peptide sequence. |
| priorityDate | 2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 162.