| abstract |
The present invention relates to the preparation of triazine, pyrimidine and pyridine derivatives of formula (I) by condensing the corresponding halo-triazine, pyrimidine or pyridine with pyridyl- or pyrimidinyl-borane in the form of Suzuki coupling ≪ / RTI > Wherein U, V, W and Z are nitrogen or carbon atoms, at least one of U, V and W is nitrogen, the other substituents are as defined herein, and the amino function is protected as formamidine. The present invention also relates to suitable intermediates and methods for preparing such intermediates. The present invention also relates to a process for the preparation of 5- (4,6-dimorpholino-1,3,5-triazin-2-yl) -4- (trifluoromethyl) pyridin- do. |