| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_832231e56616a3e87c01de72bb8aaeba |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| filingDate |
2015-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e25b0131e3e167093963b1dc41e2d865
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8af963a4555106ea846c049819bf80b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c202baac61829691e34cb9a08cb341d3 |
| publicationDate |
2016-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20160140031-A |
| titleOfInvention |
Novel TLR4 antagonist |
| abstract |
The present invention relates to a peptide for inhibiting the TLR4 signaling pathway, a TLR4 antagonist comprising the peptide, and a composition for preventing or treating autoimmune diseases and inflammatory diseases comprising the peptide. The peptide according to the present invention has excellent effect of suppressing the secretion of interleukin-6 (IL-6), NO and ROS and the activation of NFKB and MAPKs by inhibiting the TLR4 signaling pathway induced by lipopolysaccharide (LPS) And a composition for preventing or treating autoimmune diseases and inflammatory diseases caused by the TLR4 signaling pathway. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200113511-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210041401-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020141704-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021010621-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200009611-A |
| priorityDate |
2015-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |