abstract |
The present invention relates to recombinant proteins, also referred to as improved MAT (iMAT) molecules, comprising at least one dislocation module, at least one targeting module and at least one antigen module, At least one cysteine residue is substituted with a different amino acid residue. The iMAT molecule is particularly useful as a vaccine and is useful, for example, for the treatment and / or prevention of allergic and / or infectious diseases and for the prevention of transmission of infectious diseases in vivo. The invention further relates to a nucleic acid encoding said iMAT molecule, a corresponding vector and a primary cell or cell line. |