abstract |
An embodiment of the present invention relates to a composition comprising a particulate agonist for inhalation and a particulate agonist, as well as to a method of treatment, as well as a method for producing said particulate agitator and composition for inhalation. Method embodiments include preparing an emulsion by combining an oil phase dispersion of hydrophobic seed particles with an aqueous dispersion comprising an emulsifying agent and an emulsion stabilizing agent, and homogenizing the emulsion to produce a feedstock comprising the encapsulated particles And spray drying the feedstock to form a plurality of coated particles, wherein the resulting particles comprise a porous shell disposed on or in the core, wherein the core comprises one or more hydrophobic seed particles . |