| abstract |
The present invention relates to a bone binder for the prevention or treatment of periodontal disease and a method for producing the bone binder by using a dopa-Fe (III) complex based on a mussel adhesive protein loaded with a drug. The bone binder according to the present invention can be prepared by using a catechol compound-metal coordination complex, especially a mucoadhesive protein-based dopa-Fe (III) complex, so that it has excellent biocompatibility and can control the discharge rate of the loaded drug Therefore, it has an effect of preventing or treating periodontal disease and having an effect of being usefully used for implant treatment of a patient having poor bone quality. |