| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9eaa5e9d4581ea7202879b0ff2ba37fe |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-331 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-718
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L1-3002 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-718 |
| filingDate |
2015-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2d54e6192406488be189afe64e8c75e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f5aef3c4bb5eaf0d5794f71770e0167
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ecf8f9ba6493f807c8910a7374945a5 |
| publicationDate |
2016-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20160118405-A |
| titleOfInvention |
Pharmaceutical composition having angiogenesis inhibition activity comprising extract of Coptis japonica Makino |
| abstract |
The present invention relates to a pharmaceutical composition comprising an extract of Coptis japonica Makino as an active ingredient and having an activity of inhibiting angiogenesis against a vascular endothelial growth factor, Inhibits VEGF-induced vascular endothelial cell proliferation, inhibits VEGF-induced migration of vascular endothelial cells, inhibits microvascular sprouting around the aorta by VEGF And thus can be effectively used for the prevention and treatment of ocular diseases such as diabetic retinopathy, glaucoma, and cancer caused by neovascularization. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020222470-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200126913-A |
| priorityDate |
2015-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |