abstract |
The present invention generally relates to antibodies and fusion proteins of interleukin-10 (IL-10). More specifically, the present invention relates to a fusion protein of an antibody and a mutant IL-10 exhibiting improved properties for use, for example, as therapeutic agents in the treatment of inflammatory diseases. The present invention also relates to a polynucleotide encoding said fusion protein, and a vector and a host cell comprising said polynucleotide. The present invention also relates to a method of producing the fusion protein of the present invention and a method of using the same to treat diseases. |