http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160113435-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f722c54b41453cc603ae5bd1c415176 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-331 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L1-3002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-73 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-73 |
| filingDate | 2015-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b7d10ddd85c2007eab54dceb9559df6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ac777842c5ed702b554ad5072f03f69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5cbe0c820ccdb876f3496a5bd3ea8d1 |
| publicationDate | 2016-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20160113435-A |
| titleOfInvention | Pharmaceutical composition comprising the organic solvent fraction of sorbus commixta fruit as an effective component for prevention or treatment of thrombosis and health functional food comprising the same |
| abstract | The present invention relates to a process for preparing Sorbus commixta ) fruit or an organic solvent fraction obtained from an ethanol extract as an active ingredient, and to a health functional food and a pharmaceutical composition for prevention / treatment / improvement of thrombosis. The pharmaceutical composition for the prevention or treatment of thrombosis of the present invention and the hexane fraction and the ethyl acetate fraction of the Aspergillus oryzae as an active ingredient of the health functional food can be obtained by dissolving the beans in hot water or ethanol The hexane fraction and the ethyl acetate fraction are prepared by extracting and preparing a hexane fraction and an ethyl acetate fraction obtained by successively fractionating with hexene, ethyl acetate and butanol. The hexane fraction and the ethyl acetate fraction as described above are used for the production of a thrombogenic enzyme And exhibits potent antithrombotic activity by inhibiting the coagulation of platelets which plays a role of initiating thrombogenesis together with inhibition of blood coagulation factors and can be used for prevention and treatment of thrombosis such as ischemic stroke and hemorrhagic stroke through improvement of blood circulation An outstanding efficacy A. Particularly, the hexane or ethyl acetate fraction of the extract of Aspergillus oryzae according to the present invention is excellent in thermal stability and does not exhibit the effect of inhibiting blood coagulation factor and thrombogenesis-related enzyme even in an acidic condition of pH 2 and plasma, Powder, ring, tablet, etc., and can be prepared in a form that can be taken at any time. Therefore, it is an extremely useful invention in the pharmaceutical industry and the food industry. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180052157-A |
| priorityDate | 2015-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 137.