http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160110762-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a9c6fbcaf79279677eade00eb7b6e01 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-64 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B32-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48369 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48769 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B31-0206 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48238 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01B31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate | 2015-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c4c2551c090bd9aa86dd5dce69f77fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9529d5e17853112cf4ac357582a6771d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30a86699fe7d37be40ad488d3b45676a |
| publicationDate | 2016-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20160110762-A |
| titleOfInvention | Synthesis of carbon nanoparticle-polymer composite for delivery of bioactive materials and the uses thereof |
| abstract | The present invention provides a method for synthesizing a product with a faster and higher yield than a conventional method for hydrothermal reaction and / or microwave-assisted high-temperature synthesis reaction based on carbon nanoparticles coated with PEG or PEI . The microwave-assisted synthesis method includes a remarkable invention showing that the purpose of gene transfer to the synthesized particles is determined differently depending on the change in the molecular weight of the PEI used in the reaction. In the case of carbon nanoparticles coated with PEI, it was possible to conjugate various kinds of fluorescent dyes through surface modification, which showed applicability to multiple imaging systems. In the case of PEG-coated carbon nanoparticles, it is possible to apply different kinds of pharmaceutical active ingredients and genes by applying the aromatic structure inside the particles, and thus it is suitable as a form of chemotherapy treatment for tumor and / or disease cells , And the heat-generating ability by photo-sensitization at the time of near-infrared laser irradiation showed specific cytotoxicity against tumor and / or diseased cells around the particle. Therefore, the present invention is superior to the complex treatment (chemotherapy and / or photo-sensitization fever treatment) based on the carbon nanoparticles surface-coated with PEG or PEI proposed in the present invention. It is possible to conjugate the target ligand and use it as a target treatment for selectively targeting a target cell or a target tissue. In addition, excellent gene transfer efficiency to cells and / or tissues based on high biocompatibility of the particles can be utilized in fields such as basic research, beauty, and medicine. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020242268-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109135737-A |
| priorityDate | 2015-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1004.