http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160103966-A

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filingDate 2016-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_390a9bb5c790253c8eabcfdaf23e0414
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_226b95c6fc412b70cca046cd3fc3ef1a
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publicationDate 2016-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20160103966-A
titleOfInvention Microfluidic chip and a method for preparing artificial neuronal network thereon
abstract The present invention relates to a microfluidic platform for the growth of unidirectional axons and to a method for culturing in vitro neurons comprising the same. More particularly, the present invention relates to a microfluidic platform capable of forming a unidirectional artificial neural network similar to an actual brain neural network by designing asymmetric microchannels using the growth characteristics of axons, and an in vitro neuron culturing method using the microfluidic platform . By using a microfluidic cell culture platform according to the present invention, neurons are cultured in vitro to regulate the growth direction of axons, thereby overcoming the existing limitations and linking two or more nerve cells having unidirectionality It can form neural networks of neurons that actually simulate in vivo neural structures. In addition, the microfluidic platform according to the present invention can be used as a brain or brain damage model because it can produce a neural network having a directional characteristic without any additional chemical coating or additional device using the growth characteristics of the neural axon. It can also be used for drug screening.
priorityDate 2016-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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