abstract |
The present invention relates to novel substituted piperidinyl-tetrahydroquinolines, their preparation, their use for the treatment and / or prevention of diseases and their use for the manufacture of medicaments for the treatment and / or prophylaxis of diseases, Microangiopathy, diabetic limb ulcer, especially for promoting wound healing of diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular heart disease, peripheral and cardiovascular diseases, thromboembolic diseases and ischemia, peripheral circulation disorders , Raynaud's phenomenon, CREST syndrome, microcirculatory disorders, intermittent claudication, and the use thereof for the treatment and / or prevention of peripheral and autonomic neuropathy. |