| abstract |
Described herein are compositions comprising (i) a first thermoplastic polymer and a first therapeutic agent, wherein the first therapeutic agent comprises a core dissolved in the first thermoplastic polymer, and (ii) a second thermoplastic polymer, wherein the second thermoplastic Wherein the first therapeutic agent is less permeable to the first thermoplastic polymer in the polymer and comprises a second therapeutic agent in solid form wherein the second therapeutic agent is loaded onto a portion of the envelope Drug delivery system. |