| abstract |
The present invention provides a quinazoline derivative represented by the following formula (I), or a pharmaceutically acceptable salt thereof: Wherein R 1 and R 2 represent a hydrogen atom, a halogen atom, or a lower alkyl group optionally having a substituent; Z represents a cycloalkyl group having a substituent or a cycloalkenyl group having a substituent; Q represents an optionally substituted bicyclic heteroaryl group. These compounds have an inhibitory effect on the Wnt /? - catenin signaling pathway, exhibit antitumor effects, and are useful as medicines. |