| abstract |
There is provided a taxane compound having the structure of formula (I), a process for preparing the same, and a use of a composition comprising a taxane compound, a pharmaceutical salt, and a solvent thereof as an active ingredient in the preparation of an oral anticancer agent. In the formula, R 1 is -COR 6 , -COOR 6 , and -CONR 7a R 7b ; R 2 is a C 1 -C 6 alkyl, a C 1 -C 6 alkenyl group, a substituted hydrocarbon group, a heterocyclic group, an aromatic group or a substituted aromatic group; R 3 is -OR 6 , -OCOOR 6 , -OCOSR 6 , and -OCONR 7a R 7b ego; R 4 is -OR 6 , -OCOOR 6 , -OCOSR 6 , -OCONR 7a R 7b , H, and OH; R 6 is a C 1 -C 6 alkyl, a C 1 -C 6 alkenyl, a C 1 -C 6 alkynyl group, a substituted hydrocarbon group, an aromatic group, or a heterocyclic group ; And R 7a And R < 7b > are each hydrogen, a hydrocarbon group, a substituted hydrocarbon group or a heterocyclic group. (I) |