Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_259045c6eba6e2c5d338b84e0a88b571 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1307 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate |
2015-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a63bea708a9a798cdefa66d8ec0666a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37966862a361745f941fe737b252526f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc6b6ef01967c53cd8e43b8b9bb6bc56 |
publicationDate |
2016-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20160087150-A |
titleOfInvention |
Behcet's disease human cell model and use thereof |
abstract |
The present invention relates to a method for producing induced pluripotent stem cells (iPSCs) derived from Behcet's disease (BD) patients and hematopoietic progenitor cells (HPCs) differentiated therefrom, Induced pluripotent stem cells derived from fibroblasts of BD patients can be differentiated into hematopoietic progenitor cells that reproduce the characteristics of diseases that occur in BD patients. In particular, The BD human cell model and the biomarker of the present invention can be used for the analysis of the pathogenesis mechanism of BD and the development of the therapeutic agent since the gene expression and the protein secretion level of intracellular infectious cytokine and chemokine, . ≪ / RTI > |
priorityDate |
2015-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |