http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160076654-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5396826ac8c36d31e3eb53c9ef088a68 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-545 |
| filingDate | 2014-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d57561af2f35bcce18635259fa695aa0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5ecd1cd61cef8a7c423f4ef3896117c |
| publicationDate | 2016-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20160076654-A |
| titleOfInvention | Pharmaceutical composition for preventing or treating cell senescence comprising exosome |
| abstract | The present invention relates to a composition for preventing or ameliorating cell senescence comprising exosome isolated from stem cells as an active ingredient, and a composition for preventing or ameliorating cell senescence comprising, as an active ingredient, exosome isolated from stem cells of the present invention The present inventors have found that ex-somes isolated from stem cells are effective for inhibiting cell senescence, because the SA-β-gal activity is inhibited in a dose-dependent manner by exocytosis without cytotoxicity in human fibroblasts induced by aging and adriamycin And it was confirmed that cell proliferation of the cell group treated with exosome isolated from stem cells was improved. Therefore, the composition containing the exosome isolated from the stem cells of the present invention as an active ingredient can be used as a composition for treating a cell senescence-related disease and a cosmetic composition for improving skin aging. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019022451-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190090369-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200110728-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019066434-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180047952-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180048431-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190017173-A |
| priorityDate | 2014-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 185.