http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160061427-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2014-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f13d30083ad6477a7919120c39abc0ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_571a56049700f9445fe2bc753adf02d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa98399f31151b94885ad56af2aae10a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_394c27412baeea5f0bc9aacb926a544a |
| publicationDate | 2016-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20160061427-A |
| titleOfInvention | Pyrido[4,3-b]pyrazine-2-carboxamides as neurogenic agents for the treatment of neurodegenerative disorders |
| abstract | The present invention relates to compounds of the general formula (I): or a pharmaceutically acceptable acid addition salt thereof, a racemic mixture or a corresponding enantiomer and / or optical isomer thereof, (I) In this formula, R < 1 > is hydrogen; R 2 is hydrogen, lower alkyl, benzyl, lower alkyl substituted by hydroxy, or cycloalkyl optionally substituted by cyano; Or R < 1 > and R < 2 > together with the N-atom to which they are attached form a heterocycloalkyl group optionally containing additional N, O or S ring atoms, which is optionally substituted with hydroxy; R < 3 > is halogen, Phenyl optionally substituted by one or more halogens, cyano, lower alkyl substituted by halogen, lower alkoxy substituted by halogen, lower alkyl substituted by hydroxy, Lower alkyl or heteroaryl optionally substituted with halogen, 3,6-dihydro-pyran-4-yl, or Piperidinyl-1-yl optionally substituted with one or more halogens. The compounds of formula I are useful in the treatment of schizophrenia, compulsive personality disorder, depression, bipolar disorder, anxiety disorder, normal aging, epilepsy, retinal degeneration, traumatic brain injury, spinal cord injury, post traumatic stress disorder, panic disorder, Alzheimer's disease, cognitive disorders, chemotherapy-induced cognitive dysfunction, Down syndrome, autism spectrum disorders, hearing loss, tinnitus, spinal cord cerebellar ataxia, amyotrophic lateral sclerosis, multiple sclerosis, Huntington's disease, stroke, radiation therapy, Or an abuse of a neuro-active drug selected from alcohol, opiate, methamphetamine, phencyclidine and cocaine. |
| priorityDate | 2013-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 240.