abstract |
The present invention relates to a stable composition for gonadotropin. It provides a composition useful for stabilizing gonadotropins while preventing aggregation, dissociation, cleavage and formation of oxidized species variants in the injection solution. Therefore, it prevents the instability of protein or polypeptide molecules caused by aggregation or cleavage or oxidation during or after formulation. It also provides a pharmaceutical composition of gonadotropin which can be used therapeutically for the treatment of various indications in either single-dose or multi-dose forms. |