http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160045656-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd15fea28fa5c3272dd3e41dcf3b0dd3 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-107 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07049 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
| filingDate | 2016-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a090f71cb192de00e84fcf97b6fb9794 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8026f2b9544e66ce849d422a4e68494 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53ab99b4f9762ce08ea236bb8d714666 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa81fbfee8f42f3abf3ee48567f2525d |
| publicationDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20160045656-A |
| titleOfInvention | Reverse Transcriptase Having Improved Thermostability |
| abstract | The present invention relates to a reverse transcriptase having increased thermostability. More particularly, the present invention relates to a reverse transcriptase having an amino acid sequence of 63rd glutamine (Q63), 264th lysine (K264) A group consisting of 295th lysine (K295), 306th threonine (T306), 346th glutamic acid (E346), 408th proline (P408), 438th histidine (H438) and 454th asparagine (N454) Is replaced by another amino acid to thereby increase the thermal stability of the mutant reverse transcriptase. Since the mutant reverse transcriptase of the present invention exhibits excellent thermal stability compared with the wild type reverse transcriptase, even if the reverse transcription product can not be efficiently obtained due to the structural interference of a specific RNA capable of forming a stable secondary structure even at a high temperature, And the desired cDNA can be obtained. |
| priorityDate | 2016-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 696.