http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160041414-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5ad8562c578b061df7a2c3aee9d0e24 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-50 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-76 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
| filingDate | 2014-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2be9cecadffd9f027fa21dfa1df9b07 |
| publicationDate | 2016-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20160041414-A |
| titleOfInvention | Novel Turn-On Probe Conjugates with Both Acidic and Basic pH-Reactivity and Uses Thereof |
| abstract | The present invention relates to a novel turn-on probe conjugate for an enzymatic assay, and a use thereof. The probe conjugate of the present invention exhibits high fluorescent/luminescence signals under both an acidic pH (for example, pH 4 to pH 6) and a basic pH (for example, pH 8 to pH 10) conditions in comparison to the signals at neutral pH. The probe conjugate of the present invention can conveniently and efficiently detect presence of a pH-changing enzyme (for example, β-lactamase such as penicillinase or adenosine deaminase) or drug-resistant bacteria comprising the same. Therefore, a composition comprising the probe conjugate of the present invention can provide an assay system regarding pH-changing enzymes, and can be effectively used to detect infective diseases caused by drug-resistant bacteria comprising such enzymes. According to an embodiment of the present invention, the turn-on probe conjugate of the present invention comprises: (a) a pH-sensitive moiety; (b) a fluorescent moiety; and (c) a transition metal complex connecting the pH-sensitive moiety and the fluorescent moiety. |
| priorityDate | 2014-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 224.