| abstract |
The present invention relates to pharmaceutical compounds, pharmaceutical compositions and methods, particularly EGFR (including HER), proliferative diseases, cancer, tumors, inflammatory diseases, autoimmune diseases, psoriasis, dry eye or immunologically related diseases, and in some embodiments, Including but not limited to Alk, PDGFR, BLK, BMX / ETK, FLT3 (D835Y), ITK, TEC, TXK, BTK, or JAK, and diseases or disorders associated with each pathway / RTI > compositions and methods for the treatment and / |