| abstract |
The present invention provides antibodies and related molecules that bind to chemokine receptor 4 (CXCR4). The present invention also provides an antibody-drug conjugate comprising an antibody as described above, an antibody encoding nucleic acid, and a method of obtaining such an antibody. The present invention also relates to the use of said antibodies and anti-CXCR4 antibodies for the treatment of diseases associated with CXCR4 function or expression (e.g., cancer) such as colon, RCC, esophagus, stomach, head and neck, lung, ovary, pancreatic cancer or blood cancer To a method for the therapeutic use of a drug conjugate. |