abstract |
Compositions designed for mucosal application include a tonicity adjusting agent, a hydroxyalkyl methyl cellulose and a liquid diluent, wherein the hydroxyalkyl methyl cellulose has a DS of 1.6 to 2.7 and an MS of 0.40 to 1.30, wherein DS is a methoxyl group MS is the molar substitution of the hydroxyalkoxyl group and at least 55% by weight of the liquid diluent is water. When the composition further comprises a physiologically active agent, the composition may be used for transmucosal administration of the physiologically active agent to an individual. |