http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160020625-A

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filingDate 2014-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_062df14341b5d91577a93c8e159b103c
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publicationDate 2016-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20160020625-A
titleOfInvention Immediate release oral composition comprising non-steroidal anti-inflammatory drug and proton pump inhibitor, and method for preparing the same
abstract The present invention relates to an inner capsule comprising a non-steroidal anti-inflammatory drug (NSAID) and a proton pump inhibitor (PPI); And an outer capsule comprising an alkaline buffer and surrounding the inner capsule, wherein the composition of the present invention is configured in the form of a double capsule encapsulating the outer part with an alkaline buffer so that the pH of the gastric environment To increase the solubility of the pH-dependent drug, and to improve the solubility and dissolution of the drug by converting the crystalline form of the drug into an amorphous form, so that the drug can be effectively used as a rapid-acting composition without being affected by pH.
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