abstract |
The present invention relates to macrocyclic urea derivatives (I) of the general formula (I) (I) Wherein R1, R2, R3, V and Y are as defined below. The compounds of formula I are inhibitors of the TAFIa enzyme (activated thrombin activatable fibrinolysis inhibitor). The present invention further relates to processes for the preparation of compounds of formula I and their use as medicaments. |